Integrin-laminin interactions controlling neurite outgrowth from adult DRG neurons in vitro

Stefan Plantman, Manuel Patarroyo, Kaj Fried, Anna Domogatskaya, Karl Tryggvason, Henrik Hammarberg, Staffan Cullheim.

Molecular and Cellular Neuroscience, 2008

The authors examined neurite outgrowth from adult mouse DRG neurons on four laminin isoforms (laminin-1/LM-111, laminin-2/LM-211, laminin-8/LM-411 and laminin-10/LM-511) in vitro. The growth on LN111 and LN511 was trophic factor-independent and superior to the one on LN211 and LN411.